Magnetic 3D Printing Of Human Cells Could Rework Personalized Medication

Generally, when unwell the physicians write down a common treatment that fits all but imagines being given a customized medication instead for the symptoms. According to McMaster University engineers, they have used the 3-D printing technology to develop artificial tumors so as to make it possible for the researchers to test novel therapies and drugs and in turn lead to the development of personalized medicine. For investigating human health, the currently available tests are quite expensive and time-intensive. In most of the research, for a better understanding of the disease or drug a single layer of animal or human cells are used in the laboratory environments. These 2D models are used to test the effect of the drug on the human cells and the animal models help gist out the progression of the disease.

3D printing technology helps print realistic 3D models with more than a single layer of cell clusters and exact replica to the body cells for an accurate experimental analysis of the drugs. If this technology is to thrive then the potential use of animal models in testing could be completely eliminated. The lead researcher Ishwar K. Puri along with his squad has created the method wherein the magnets are used to speedily print 3-D cell clusters. The magnetic property consisting materials like the cells show stronger attraction towards the magnetic whereas the weaker materials are repelled away. The differences in the magnetic susceptibilities of materials assist focus on one within a volume.

The team was able to build 3-D cancer tumors in just 6 Hours using the novel method. The use of magnetic salt hydrate, Gd-DTPA, in the medium affirmed to be nontoxic to cells and have proved positive on highly intricate bioinks to print cell groups that are an exact copy of the human tissues. The researchers plan to create tumors containing cancer cells using 3-D printing for analyzing drugs effect on artificial tumors. 3-D printing of human-like cell clusters paves a new way for the artificial synthesis of multiple tissues and organs. Wake Forest Institute for Regenerative Medicine (WFIRM) scientists constructed a mobile skin bioprinting system that prints layer-by-layer of skin directly on the wound. This is the first of its kind on-site management device that can scan and measure the wound for faster healing in the burnt and diabetic pressure ulcer patients.

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